منابع مشابه
Metabolic effect of phenylbutazone in gouty and non-gouty arthritis.
Phenylbutazone ("Butazolidin") is an effective therapeutic agent in acute gouty arthritis (Kuzell and co-workers, 1952, 1954; Kidd, Boyce, and Freyberg, 1952, 1953; Stephens, Yeoman, Holbrook, Hill, and Goodin, 1952; Steinbrocker, Berkowitz, Ehrlich, Elkind, and Carp, 1952; Engleman, Krupp, Forsham, Griffin, Johnson, Green, and Goldfien, 1953). It is a synthetic pyrazol derivative, with the che...
متن کاملPathogenesis and Clinical Management of Gouty Arthritis.
Gout, the most common of the crystal arthritides is a result of disturbed uric acid metabolism and precipitation of urate crystals in extra cellular space of joints, periarticular tissue, bones and other organs. In the West, gout affects around 1% of adult men over 45 years of age. The estimated incidence being 0.6 to 2.1 per 1000 per year, with a prevalence of 9.5 to 13.5 per 1000 persons of a...
متن کاملGouty inflammation confused with septic arthritis.
A 65-year-old woman came to the emergency department for continuous pain and swelling at the ulnar dorsal margin of the right fifth metacarpophalangeal joint which had lasted 4 days. The patient had no other signs in the rest of the joints of the hands or the rest of the skeleton. At the onset of symptoms, the patient went to her family physician, who prescribed antibiotics, but after noting no...
متن کاملCurrent Management Concepts in Gouty Arthritis
BackgroundGouty arthritis is an extremely painful condition that causes functional impairment. Longstanding elevation of the serum uric acid level can lead to the deposition of monosodium urate crystals, causing gout (arthritis, urate nephropathy, tophi). Gouty arthritis has become increasingly complex because of multiple comorbidities, iatrogenic factors and hyperuricemia that is refractory to...
متن کاملGouty Arthritis: New Targets for Future Therapies
Gout is a very painful arthritis that affects millions of people around the world. In the last decade, various mechanisms associated to uric acid crystals-induced joint inflammation have been described, including details related to the activation of the cytoplasmic sensor NLRP3 inflammasome that eventually leads to the maturation and release the cytokine IL-1β. The identification of these signa...
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ژورنال
عنوان ژورنال: Journal of the Korean Medical Association
سال: 2003
ISSN: 0023-4028
DOI: 10.5124/jkma.2003.46.4.357